WHY IS IT IMPORTANT TO SUSPECT IFIs?
IFIs are life-threatening conditions caused by yeasts or moulds with high mortality rates that range from 40–100% in patients who are immunocompromised, or have an underlying condition.1-6 Treatment can be challenging as a number of fungi responsible for these infections are resistant to many available antifungals, including azole and echinocandin options.7,8 The timely diagnosis of these serious infections is crucial; however, the signs and symptoms are often non-specific and similar to those of bacterial or viral infections. Furthermore, access to modern diagnostic tools or biomarkers can be limited, delaying the initiation of an appropriate treatment.9,10
Time is of the essence in the fight against IFIs.
HOW IS THE FUNGAL LANDSCAPE CHANGING?
Difficult-to-treat fungal pathogens are emerging worldwide, and have become more frequent than in previous years.7,8 Explore the changing trends and epidemiology across the world to help you manage a variety of IFIs.
IFIs can lead to a spectrum of other life-threatening conditions, such as sepsis or pneumonia.11-19 Learn about the most serious manifestations of IFIs, their epidemiology, prognosis, and risk factors.
Date of preparation: November 2022. Job code IHQ-AMB-0813.